Information for pharmacists

For UK healthcare professionals only

Product Information Kolanticon

Kolanticon is a white viscous suspension containing 2.5mg dicycloverine hydrochloride, 200mg aluminium hydroxide, 100mg light magnesium oxide, 20mg simethicone per 5ml.


Treatment and prophylaxis of symptoms of peptic ulcer and functional dyspepsia especially in patients in whom gastric distress
results from hyperacidity, smooth muscle spasm, including irritable bowel syndrome (IBS), and flatulence. Also indicated for
symptomatic relief in oesophagitis, hiatus hernia, gastritis and iatrogenic gastritis.


For oral use. Two to four 5ml spoonfuls every four hours as required. Care should be taken in patients with renal insufficiency and also patients on low phosphorous diets.


Antimuscarinics share the toxic potential of atropine, and the usual precautions associated with atropine therapy should be observed with these agents.  All antimuscarinics have the potential to:

  • Inhibit parasympathetic control of the urinary bladder and gastrointestinal tract, causing urinary retention or constipation
  • Suppress intestinal motility and relax the lower esophageal sphincter
  • Increase intraocular pressure (especially in patients with angle-closure glaucoma)

Kolanticon is therefore contraindicated in the following conditions due to the potential of dicycloverine to bring about unwanted antimuscarinic effects.

Obstructive uropathy, obstructive disease of the gastro-intestinal tract, paralytic ileus and intestinal atony, glaucoma, prostatic enlargement, severe ulcerative colitis, myasthenia gravis, known hypersensitivity to any of the ingredients.

Warnings and Precautions

In the presence of renal insufficiency magnesium salts may cause central nervous system depression. Aluminium hydroxide in the presence of low phosphorous diets may cause phosphorous deficiency. Aluminium hydroxide may reduce absorption of tetrayclines when given concomitantly. Use with care in patients with hiatus hernia associated with reflux oesophagitis because anticholinergic drugs may aggravate this condition.

Take care if the patient is taking any concomitant medications or if they suffer from kidney disease. Also advise the patient to consult their doctor if symptoms persist or worsen.


Antacids may interfere with the absorption of tetracyclines, ACE inhibitors, digoxin, rifampicin, ketoconazole, penicillamine, ciprofloxacin (and other quinolones), anticoagulents and biphosphonates, if given concurrently. Because of the large number of possible interactions they should not be given at the same time as any other drugs.

Undesirable Effects

In particularly sensitive patients dicycloverine hydrochloride may cause atropine-like side-effects such as dry mouth, blurred vision, urinary retention or constipation.

Pack size and retail price

200ml bottle retail price: £3.89, 500ml bottle retail price: £4.92 PL 15760/0004. Legal category: P. Licence holder: Peckforton Pharmaceuticals Ltd, Crewe Hall, Crewe, Cheshire, CW1 6UL.

PIP Codes

200ml 007 – 7362
500ml 015 – 0524

For more detailed information please refer to the Summary of Product Characteristics